Sunday, May 7, 2017

Is an epidural right for you?

We will start with the basics with this post in order to be thorough. Before you begin reading, yes, I know there is A LOT of information. There is A LOT of studies I am sighting. And yes, it will take you a moment to read this entire post. BUT, Ive included this information as I feel its of the utmost importance for the informed mother. This will help mothers get a more depth idea if an epidural is right for them or not. I encourage you to proceed with this post when you have a few minutes to actually devote your full attention to the information presented. 

What is an epidural?
Epidural anesthesia is a regional anesthesia that blocks pain in a particular region of the body. The goal of an epidural is to provide analgesia, or pain relief, rather than anesthesia, which leads to total lack of feeling. Epidurals block the nerve impulses from the lower spinal segments.

How is an epidural administered?
An anesthesiologist injects the paid medication into the epidural space of the spinal cord

Once you give the go-ahead for an epidural, you’ll first be hooked up to IV fluids, which will prevent the drop in blood pressure that commonly happens during the procedure. Depending on your delivering hospital’s policies, you might also be hooked up to a urinary catheter at this point, since getting out of bed may not be an option once you get your epidural.

To prep you for the main needle, you'll receive local anesthesia on a small area of your low to mid back, which will be sterilized with antiseptic. Once you're numb, you'll be asked to sit on the side of your bed hunched over, while a large needle is inserted into the epidural space. (You will want to ask your doctor about hospital procedure to see who is still allowed in the room with you while you get your epidural. In my hospital, they didnt allow my partner or doula. Only a nurse was able to offer support through labor.)Some women feel nothing at this point, while others report feeling pressure, tingling or momentary pain. My account of getting an epidural was that it felt like my kidneys were going to burst. It was more painful than the labor I was going through. (Keep in mind, they don't always get it on the first try. You have to sit very still, WHILE IN ACTIVE LABOR, for them to put in an epidural. If they miss, they will have to do it a second time. Or even more if they still can't get it.) Once the needle is in place, the anesthesiologist inserts a catheter (the fine tubing through which the drug is delivered). The needle is then removed, the catheter is taped in place, and you'll be able to lie down again. Another word of advice is you have to be careful not to lay on the catheter in such a way that it kinks or bends it. Otherwise it will prevent the medication from flowing into your back. From there it should be smooth sailing.... or at least much less painful. Another thing to keep in mind is that epidurals don't always numb everything. Sometimes you can still feel parts of your body while other parts are numb. Naturally, after having an epidural, you are now confined to a bed and cannot walk around. One last bit of information. Many mothers I have talked to who have had epidurals in the past will tell me they still feel the pinch in their back several years later when its cold. I personally haven't felt that during any kind of specific weather. I have however felt only what I can describe as a muscle spasm right where I had my epidural. It doesn't seem to have anything specifically that triggers it for me. It just sort of happens randomly a few times a month. It only lasts a couple seconds and then it passes. Im not sure if anyone else has encountered that kind of lasting effect, but thats just my personal encounter.

When can you have an epidural?
You'll definitely need to be in active labor to get an epidural. Anything prior to that may either not be true labor or you could be getting it much too soon and it will stall labor. What is considered active labor? You'll have to be around 4-5cm and be having regular contractions for several hours.

When is it too late for an epidural?
Your labor and delivery team may urge you not to request pain relief if they think you'll deliver your baby soon. They may have the idea that the reduced sensation could make it harder for you to push your baby out and increase your odds of needing a vacuum extraction, forceps delivery or c-section. 

Tattoos and epidurals
If you've gotten a lower-back tattoo, it shouldn't stop your anesthesiologist from giving you an epidural during labor. Though you might have heard that the dye in the tattoo can be picked up by the epidural or spinal-block needle and carried into the spinal fluid or bloodstream, it can't. Dye in a healed tattoo is fixed inside the skin. Plus, ink is chemical inert - in other words, totally harmless to the body - so even if it could enter the spine or bloodstream (highly unlikely in the first place), it wouldn't have any adverse effects.

Your Anesthesiologist may legitimately balk, however, if your tattoo is just a few weeks old (hope not, since getting a tattoo during pregnancy isn't the best idea to begin with) and the skin is still red and inflamed (tattooed skin takes at least two weeks to heal). Poking an epidural needle through a raw tattoo can boost the chances of an infection, and the anesthesiologist won't want to take that risk.

Even with a well-healed tattoo, your anesthesiologist may opt to give you the epidural through a patch of undecorated skin to eliminated the very small risk that the injection will cause a scar that will disfigure your artwork. Not sure how your anesthesiologist will react? Talk to your doctor or the hospital before you go into labor to make sure your tattoo won't raise any issues. 

Risks and concerns of getting an epidural
Epidurals significantly interfere with some of the major hormones of labor and birth, which may explain their negative effect on the processes of labor. As the World Health Organization comments, “epidural analgesia is one of the most striking examples of the medicalization of normal birth, transforming a physiological event into a medical procedure.”
For example, oxytocin, known as the hormone of love, is also a natural uterotonic—a substance that causes a woman’s uterus to contract in labor. Epidurals lower the mother’s production of oxytocin, or stop it's normal rise during labor. The effect of spinals on oxytocin release is even more marked. Epidurals also obliterate the maternal oxytocin peak that occurs at birth —the highest of a mother’s lifetime—which catalyses the final powerful contractions of labor and helps mother and baby to fall in love at first meeting. Another important uterotonic hormone, prostaglandin F2 alpha, is also reduced in women using an epidural.
Beta-endorphins are the stress hormones that build up in a natural labor to help the laboring woman to transcend pain. Beta-endorphins are also associated with the altered state of consciousness that is normal in labor. Being “on another planet,” as some describe it, helps the mother-to-be to work instinctively with her body and her baby, often using movement and sounds. Epidurals reduce the laboring woman’s release of beta-endorphins. Perhaps the widespread use of epidurals reflects our difficulty with supporting women in this altered state, and our cultural preference for laboring woman to be quiet and acquiescent.
Adrenaline and noradrenaline (epinephrine and norepinephrine, collectively known as catecholamines, or CAs) are also released under stressful conditions, and levels naturally increase during an unmedicated labor. At the end of an undisturbed labor, a natural surge in these hormones gives the mother the energy to push her baby out, and makes her excited and fully alert at first meeting with her baby. This is known as the fetal ejection reflex.
However, labor is inhibited by very high CA levels, which may be released when the laboring woman feels hungry, cold, fearful, or unsafe. This makes evolutionary sense: If the mother senses danger, her hormones will slow or stop labor and give her the time to flee to find a safer place to birth.
Epidurals reduce the laboring woman’s release of CAs, which may be helpful if high levels are inhibiting her labor. However, a reduction in the final CA surge may contribute to the difficulty that women laboring with an epidural can experience in pushing out their babies, and the increased risk of instrumental delivery (forceps and vacuum) that accompanies the use of an epidural (see below).

Effects on the process of labor

Epidurals slow labor, possibly through the above effects on the laboring woman’s oxytocin release, although there is also evidence from animal research that the local anesthetics used in epidurals may inhibit contractions by directly affecting the muscle of the uterus.

On average, the first stage of labor is 26 minutes longer in women who use an epidural, and the second, pushing stage is 15 minutes longer. Loss of the final oxytocin peak probably also contributes to the doubled risk of an instrumental delivery—vacuum or forceps—for women who use an epidural, although other mechanisms may be involved.
For example, an epidural also paralyses the laboring woman’s pelvic floor muscles, which are important in guiding her baby’s head into a good position for birth. When an epidural is in place, the baby is four times more likely to be persistently posterior (POP or face up) in the final stages of labor—in one study, 13 percent compared to 3 percent for women without an epidural. A POP position decreases the chance of a spontaneous vaginal delivery (SVD). In one study, only 26 percent of first-time mothers (and 57 percent of experienced mothers) with POP babies experienced a SVD; the remaining mothers had an instrumental birth (forceps or vacuum) or a cesarean.
Anesthetists have hoped that a low-dose or combined spinal epidural would reduce the chances of an instrumental delivery, but the improvement seems to be modest. In one study, the Conventional Obstetric Mobile Epidural Trial (COMET), 37 percent of women with a conventional epidural experienced instrumental births, compared with 29 percent of women using low-dose epidurals and 28 percent of women using CSEs.
For the baby, instrumental delivery can increase the short-term risks of bruising, facial injury, displacement of the skull bones, and cephalohematoma (blood clot under the scalp). The risk of intracranial hemorrhage (bleeding inside the brain) was increased in one study by more than four times for babies born by forceps compared to spontaneous birth, although two studies showed no detectable developmental differences for forceps-born children at five years old. Another study showed that when women with an epidural had a forceps delivery, the force used by the clinician to deliver the baby was almost twice the force used when an epidural was not in place.
Epidurals also increase the need for synthetic oxytocin (Syntocinin, Pitocin) to augment labor, due to the negative effect on the laboring woman’s own release of oxytocin. Women laboring with an epidural in place are almost three times more likely to be administered Pitocin. The combination of epidurals and Pitocin, both of which can cause abnormalities in the fetal heart rate (FHR) that indicate fetal distress, markedly increases the risk of operative delivery (forceps, vacuum, or cesarean delivery). In one Australian survey, about half of first-time mothers who were administered both an epidural and Pitocin had an operative delivery.
The impact of epidurals on the risk of cesarean is controversial; differing recent reviews suggest no increased risk and an increase in risk of 50 percent. The risk is probably most significant for women having an epidural with their first baby.
Note that the studies used to arrive at these conclusions are mostly randomized controlled trials in which the women who agree to participate are randomly assigned to either epidural or non-epidural pain relief. Non-epidural pain relief usually involves the adminstration of opiates such as meperidine (pethidine). Many of these studies are flawed from high rates of crossover—women who were assigned to nonepidurals but who ultimately did have epidurals, and vice versa. Also, note that there are no true controls—that is, women who are not using any form of pain relief—these studies cannot tell us  about the impact of epidurals compared to birth without analgesic drugs.

Epidural techniques and side effects

The drugs used in labor epidurals are powerful enough to numb, and usually paralyze, the mother’s lower body, so it is not surprising that there can be significant side effects for mother and baby. These range from minor to life-threatening and depend, to some extent, on the specific drugs used.
Many of the epidural side effects mentioned below are not improved with low-dose or walking epidurals, because women using these techniques may still receive a substantial total dose of local anesthetic, especially when continuous infusions and/or patient-controlled boluses (single large doses) are used. The addition of opiate drugs in epidurals or CSEs can create further risks for the mother, such as pruritus (itching) and respiratory depression (see below).

Maternal side effects

The most common side effect of epidurals is a drop in blood pressure. This effect is almost universal, and usually preempted by administering IV fluids before placing an epidural. Even with this “preloading,” episodes of significant low blood pressure (hypotension) occur for up to half of all woman laboring with an epidural, especially in the minutes following the administration of a drug bolus. Hypotension can cause complications ranging from feeling faint to cardiac arrest, and can also affect the baby’s blood supply (see below). Hypotension can be treated with more IV fluids and, if severe, with injections of epinephrine (adrenaline).
Other common side effects of epidurals include: inability to pass urine (and requirement for a urinary catheter) for up to two-thirds of women; itching of the skin (pruritus) for up to two-thirds of women administered an opiate drug via epidural; shivering for up to one in three women; sedation for around one in five women; and nausea and vomiting for one in 20 women.
Epidurals can also cause a rise in temperature in laboring women. Fever over 100.4º F (38º C) during labor is five times more likely overall for women using an epidural; this rise in temperature is more common in women having their first babies, and more marked with prolonged exposure to epidurals. For example, in one study, 7 percent of first-time mothers laboring with an epidural were feverish after six hours, increasing to 36 percent after 18 hours. Maternal fever can have a significant effect on the baby (see below).
Opiate drugs, especially administered as spinals, can sometimes cause unexpected breathing difficulties for the mother, which may come on hours after birth and may progress to have serious effects. One author comments, “Respiratory depression remains one of the most feared and least predictable complications of . . . intrathecal [spinal] opioids.”
Many observational studies have found an association between epidural use and bleeding after birth (postpartum hemorrhage). For example, a large UK study found that women were twice as likely to experience postpartum hemorrhaging when they used an epidural in labor. This may be related to the increase in instrumental births and perineal trauma (causing bleeding), or may reflect some of the hormonal disruptions mentioned above, including increased risks of exposure to synthetic oxytocin.
An epidural gives inadequate pain relief for 10 to 15 percent of women, and the epidural catheter needs to be reinserted in about 5 percent. For around 1 percent of women, the epidural needle punctures the dura (dural tap); this usually causes a severe headache that can last up to six weeks, but can usually be treated by an injection into the epidural space.
More serious side effects are rare. If the epidural drugs are inadvertently injected into the bloodstream, local anesthetics can cause toxic effects such as slurred speech, drowsiness, and, at high doses, convulsions. This occurs in around one in 2,800 epidural insertions. Overall, life-threatening reactions occur for around one in 4,000 women. Death associated with an obstetric epidural is very rare, but can be caused by cardiac or respiratory arrest, or by an epidural abscess that develops days or weeks afterward.
Later complications include weakness and numbness in 4 to 18 per 10,000 women, most of which resolve spontaneously within three months. Longer-term or permanent problems can arise from: damage to a nerve during epidural placement; from abscess or hematoma (blood clot), which can compress the spinal cord; and from toxic reactions in the covering of the spinal cord, which can lead to paraplegia.

Side effects for the baby

Some of the most significant and well-documented side effects for the unborn baby (fetus) and newborn derive from effects on the mother. These include, as mentioned above, effects on her hormonal orchestration, blood pressure, and temperature regulation. As well, epidural drugs can cause directly toxic effects to the fetus and newborn, whose drug levels may be even higher than the mother’s drug levels.

Neurobehavioral effects

The effects of epidural drugs on newborn neurobehavior (behavior that reflects brain state) are controversial. Older studies comparing babies exposed to epidurals with babies whose mothers received no drugs have found significant neurobehavioral effects, whereas more recent findings from randomized controlled trials (which, as noted, compare epidural- and opiate-exposed newborns) have found no differences. However these older studies also used the more comprehensive (and difficult to administer) Brazelton Neonatal Behavioral Assessment (NBAS, devised by pediatricians), whereas more recent tests have used less complex tests, especially the Neurologic and Adaptive Capacity Score (NACS, devised by anesthesiologists), which aggregates all data into a single figure and which has been criticized as insensitive and unreliable.
For example, all three studies comparing epidural-exposed with unmedicated babies, and using the NBAS, found significant differences between groups:
Anne Murray et al. compared 15 unmedicated with 40 epidural-exposed babies, and found that the epidural babies still had a depressed NBAS score at five days, with particular difficulty controlling their state. The 20 babies whose mothers had received oxytocin as well as an epidural had even more depression of NBAS scores, which may be explained by their babies’ higher rates of jaundice. At one month, epidural mothers found their babies “less adaptable, more intense and more bothersome in their behavior.” These differences could not be explained by the more difficult deliveries and subsequent maternal-infant separations associated with epidurals.
Carol Sepkoski et al. compared 20 epidural babies with 20 unmedicated babies, and found less alertness and ability to orient for the first month of life. The epidural mothers spent less time with their babies in hospital, which was in proportion to the total dose of bupivacaine administered.
Deborah Rosenblatt tested epidural babies with NBAS over six weeks and found maximal depression on the first day. Although there was some recovery, at three days epidural babies still cried more easily and more often; aspects of this problem (“control of state”) persisted for the full six weeks.
Although these older studies used conventional epidurals, the total dose of bupivacaine administered to the mothers (in these studies, mean doses of 61.6 mg, 112.7 mg, and 119.8 mg, respectively) was largely comparable to more recent low-dose studies (for example, 67.5 mg, 91.1 mg, and 101.1 mg).
These neurobehavioral studies highlight the possible impact of epidurals on newborns and on the evolving mother-infant relationships. In their conclusions, The researchers express concernabout “The importance of first contact with a disorganized baby in shaping maternal expectations and interactive styles . . . ”

Animal studies

Animal studies suggest that the disruption of maternal hormones caused by epidurals, described above, may also contribute to maternal-infant difficulties. Researchers who administered epidurals to laboring sheep found that the epidural ewes had difficulty bonding to their newborn lambs, especially those in first lambing with an epidural administered early in labor.
There are no long-term studies of the effects of epidural analgesia on exposed human offspring. However, studies on some of our closest animal relatives give cause for concern. Golub administered epidural bupivacaine to pregnant rhesus monkeys at term, and followed the development of the exposed offspring to age 12 months (equivalent to four years in human offspring). She found that milestone achievement was abnormal in these monkeys: at six to eight weeks they were slow in starting to manipulate, and at ten months the increase in “motor disturbance behaviors” that normally occurs was prolonged. The author concludes, “These effects could occur as a result of effects on vulnerable brain processes during a sensitive period, interference with programming of [normal] brain development by endogenous [internal] agents or alteration in early experiences.”

Breastfeeding

As with neurobehavior, effects on breastfeeding are poorly studied, and more recent randomized controlled trials comparing exposure to epidural and opiate drugs are especially misleading because opiates have a well-recognized negative effect on early breastfeeding behavior and success.
Epidurals may affect the experience and success of breastfeeding through several mechanisms. First, the epidural-exposed baby may have neurobehavioral abnormalities caused by drug exposure that are likely to be maximal in the hours following birth—a critical time for the initiation of breastfeeding. Recent research has found (rather obviously) that the higher the newborn’s neurobehavior score, the higher their score for breastfeeding behavior.
In another study, the baby’s breastfeeding abilities, as measured by the Infant Breastfeeding Assessment Tool (IBFAT), were highest among unmedicated babies, lower for babies exposed to epidurals or IV opiates, and lowest for babies exposed to both. Infants with lower scores were weaned earlier, although overall, similar numbers in all groups were breastfeeding at six weeks. In other research, babies exposed to epidurals and spinals were more likely to lose weight in the hospital, which may reflect poor feeding efficiency. Other research has suggested that newborn breastfeeding behavior and NACS score may be normal when an ultra-low-dose epidural is used, although even in this study, babies with higher drug levels had lower neurobehavior (NACS) scores at two hours.
Second, epidurals may affect the new mother, making breastfeeding is more difficult. This is likely if she has experienced a long labor, an instrumental delivery, or separation from her baby, all of which are more likely following an epidural. Hormonal disruptions may also contribute, as oxytocin is a major hormone of breastfeeding.
One study found that babies born after epidurals were less likely to be fully breastfed on hospital discharge; this was an especial risk for epidural mothers whose babies did not feed in the first hour after birth. A Finnish survey records that 67 percent of women who had labored with an epidural reported partial or full formula-feeding in the first 12 weeks compared to 29 percent of nonepidural mothers; epidural mothers were also more likely to report having “not enough milk.”
Two groups of Swedish researchers have looked at the subtle but complex breastfeeding and pre-breastfeeding behavior of unmedicated newborns. One group has documented that, when placed skin-to-skin on the mother’s chest, a newborn can crawl up, find the nipple, and self-attach. Newborns affected by opiate drugs in labor or separated from their mothers briefly after birth lose much of this ability. The other Swedish group found that newborns exposed to labor analgesia (mostly opiates, but including some epidural-affected newborns) were also disorganized in their pre-feeding behavior—nipple massage and licking, and hand sucking—compared to unmedicated newborns.

Satisfaction with birth

Obstetric care providers have assumed that control of pain is the foremost concern of laboring women, and that effective pain relief will ensure a positive birth experience. In fact, there is evidence that the opposite may be true. Several studies have shown that women who use no labor medication are the most satisfied with their birth experience at the time, at six weeks, and at one year after the birth. In a UK survey of 1,000 women, those who had used epidurals reported the highest levels of pain relief but the lowest levels of satisfaction with the birth, probably because of the higher rates of intervention.
Finally, it is noteworthy that caregiver preferences may to a large extent dictate the use of epidurals and other medical procedures for laboring women. One study found that women under the care of family physicians with a low mean use of epidurals were less likely to receive monitoring and Pitocin, to deliver by cesarean, and to have their baby admitted to newborn special care.
Information taken from Sarah Buckly MD
Reasons you CANT have an epidural
  • You are taking certain medicationsMedications that you take can effect how likely you are to be able to get an epidural. The biggest culprit is blood thinners.
  • Your blood work isn't just rightIf you have a low platelet count or sometimes other problems with your blood work may make the placement of an epidural more risky.
  • The doctor can't find the right space. Sometimes, due to the normal growth of your back, your weight or back problems, including scoliosis, it may be impossible for the anesthesiologist to find the epidural space. Therefore an epidural with scoliosis may not work.
  • You are bleeding heavily. If you are bleeding heavily or are suffering from shock, you will not be given an epidural for safety reasons. Since many women tend to have lower blood pressure with an epidural, this may be made even more dangerous with the lowered blood pressure of some of these problems.
  • You have an infection of the back. It is not in your best interest to have your anesthesiologist place an epidural through an area that is infected. This can cause the infection to spread to the spine and other areas of your body and can potentially cause a great deal of damage.
  • No anesthesiologist is available. Your hospital may only have an anesthetist available during certain hours of the day or days of the week. You may also have an anesthesia department that covers an entire hospital and not just the labor and delivery unit.
  • Labor restrictions. Some hospitals will place restrictions on when you can have an epidural. It may be that you must be at a certain point in labor, like four (4) centimeters before an epidural can be given. Other hospitals may decide that epidural should not be given after a certain point of labor, for example when you've reached full dilation (10 centimeters).

What to Do if the Doctor Says No Epidural

You might be able to find out beforehand that an epidural is not in your laboring future. If this happens you are able to prepare by looking at other methods of pain relief for labor. A good childbirth class that focuses on many different types of pain relief from medications to natural forms of relief of pain may be the best option for filling your birth bag with many tools to cope with labor, particularly for the surprise revelation that you can't have an epidural.
Enlist support for getting through labor. Labor is hard work, with or without pain medications. Consider hiring a doula, even if you prefer an epidural. A professional labor assistant can help you and your partner through different pain relief optionsincluding natural pain relief like relaxationpositioning, massage, etc. She will also be trained in letting you know what your other options are for pain relief like Transcutaneous Electrical Nerve Stimulation (TENS)IV medications, etc.
If you are concerned about these issues be sure to talk to your doctor or midwife about your fears. It's also possible and highly recommended in some cases to actually visit the hospital and have a consultation with the anesthesiology department.
They may do a physical exam of your spine, take a medical history, etc. This can help answer questions you may have about epidurals and labor. Being informed ahead of time is your best solution.

Epidurals have possible benefits but also significant risks for the laboring mother and her baby. These risks are well documented in the medical literature, but may not be disclosed to the laboring woman. Women who wish to avoid the use of epidurals are advised to choose carers and models of care that promote, support, and understand the principles and practice of natural and undisturbed birth. But they have also been very helpful for laboring mothers for ages. Weather one is right for you or not is completely up to you. Keep in mind you may have set your mind one way or another and you find that in the midst of labor you change your mind. That is ok. You must do what is right for you and your baby.